The 101 Freeway is the main highway through Ventura. It actually has three nicknames through Ventura: the Ventura Freeway, the Pacific Coast Highway (PCH), and El Camino Real.
Since the 101 goes west to east through Ventura County, it confuses many residents' sense of direction as the signs say North and South.
| Southbound Exits | Northbound Exits |
| Main Street | |
| Highway 33 | Highway 33 |
| Ventura Avenue | California Street |
| Sanjon Road | |
| Seaward/Harbor | Seaward/Harbor |
| 126 Freeway | |
| Main Street | |
| 126 Freeway | |
| Telephone Road (Main) | Telephone Road |
| Victoria Avenue | Victoria Avenue |
| Johnson Drive | Johnson Drive |
